| Category: |
Gastroenterology & Hepatology |
|---|---|
| Test Code: | 169 |
| Disease: | Autoimmune Liver Diseases |
| Methodology: | Indirect Immunofluorescence |
| Substrate: | Mouse kidney/liver/stomach |
| Reference Range: | Negative: <1:10 |
| CPT Code: | 86376 |
| Schedule / Turnaround Time: | Assay performed once per week. Report availability is within one week from the time of specimen receipt. |
| Specimen Requirements: |
Specimen need not be refrigerated or frozen. Collect 2-3 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into white tube provided with Immco Diagnostics’ collection kits. If separation facilities are not available, the blood can be sent in the tube used for collection. |
| Sample Stability: |
Sample is stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8˚C) up to five days and frozen (-20˚C or lower) up to one year. |
| Relevance: |
Anti-liver cytosol type 1 autoantibodies have been reported in association with anti-LKM-1 autoantibodies in 30% of individuals with LKM-1 positive AIH. In 10% of cases, anti-LC-1 antibodies are the only liver-related circulating autoantibodies. |