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Islet Cell
Technology : IFA ~ Diabetes Brand : MarDx® ~ Diabetes Analyte : Autoimmune ~ Endocrine Diseases Intended UseThese reagents are intended for use in the detection and quantitation of IgG antibody in human sera to monkey pancreas islet cells by the indirect fluorescent antibody (IFA) procedure. The Anti-Islet Cell Antibody IFA Test System is not to be used for diagnostic purposes and is intended to be used only when the actual diagnosis is based on an established method or procedure including clinical findings. The test system is for Professional Use Only.PrincipleThe indirect fluorescent antibody test is used for the detection of human IgG antibody to the antigens of monkey pancreas islet cells. Tissue is placed in the wells of specially prepared microscope slides. Dilutions of patient sera are placed on the wells where antibody, if present, binds to the antigen. The reaction is visualized through the use of a conjugate. The conjugate is fluorescein isothiocyanate (FITC) labeled, anti-human IgG (gamma chain specific). Excitation of the FITC by ultraviolet (UV) light causes this dye to emit longer, visible, wavelengths of light in the yellow-green portion of the color spectrum. The conjugate will bind with human IgG antibodies attached to the antigens causing fluorescence when viewed through a microscope equipped with a UV light source.Product Code : 10-5548 Format : MarDx® 4 Wells Test/Kit : 48 tests CE : Cleared Additional Information :
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