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Skin Antibody
Technology : IFA ~ Skin Diseases (Bullous Pemphigus & Pemphigmoid) Brand : MarDx® ~ Skin Diseases (Bullous Pemphigus & Pemphigmoid) Analyte : Autoimmune ~ Muscle - Skin Disorders Intended UseThese reagents are intended for use in the detection and quantitation of IgG antibody in human sera to intercellular substance and basement membrane of monkey esophagus tissue by the indirect fluorescent antibody (IFA) procedure. High Complexity Test.PrincipleThe indirect fluorescent antibody test is used for the detection of human IgG antibody to the antigens of monkey esophagus intercellular substance and basement membrane. Tissue is placed in the wells of specially prepared microscope slides. Dilutions of patient sera are placed on the wells where antibody, if present, binds to the antigen. The reaction is visualized through the use of a conjugate. The conjugate is fluorescein isothiocyanate (FITC) labeled, anti human IgG (gamma chain specific). Excitation of the FITC by ultraviolet (UV) light causes this dye to emit longer, visible, wavelengths of light in the yellow-green portion of the color spectrum. The conjugate will bind with human IgG antibodies attached to the antigens causing fluorescence when viewed through a microscope equipped with a UV light source.Product Code : 10-5348 Format : MarDx® 4 Wells Test/Kit : 48 tests FDA : Cleared CE : Cleared Additional Information : Insert Version : MDN 04-0034 rev 6
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